R & d là gì

admin 25/01/2022

Biological Activity for (R)-ZINC 3573

(R)-ZINC 3573 is a Mas-related G protein-coupled receptor X2 (MRGPRX2) agonist (EC50 = 0.74 μM), which displays selectivity for MRGPRX2 over 350 other GPCRs, including MRGPRX1. (R)-ZINC 3573 induces intracellular calcium release & degranulation in LAD2 mast cells in vitro.

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Negative control (S)-ZINC 3573 (Cat. No. 6352) also available.

External Portal Information for (R)-ZINC 3573

Chemicalprobes.org và the Chemical Probes webpages of the Structural Genomics Consortium are portals that offer independent guidance on the selection and/or application of small molecules for research. The use of (R)-ZINC 3573 is reviewed on chemicalprobes.org and the SGC website.

Compound Libraries for (R)-ZINC 3573

(R)-ZINC 3573 is also offered as part of the yeahflashback.comcreen 2.0 Max. Find out more about compound libraries available from yeahflashback.com.

Technical Data for (R)-ZINC 3573

M. Wt	307.4
Formula	C18H21N5
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	2089389-15-9
PubChem ID	95882507
InChI Key	XKBSPAZCFAIBJL-OAHLLOKOSA-N
Smiles	CN(H>1CN(C2=CC(C3=CC=CC=C3)=NC4=CC=NN24)CC1)C

The technical data provided above is for guidance only. For batch specific data refer to lớn the Certificate of Analysis.

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Solubility Data for (R)-ZINC 3573

Solvent Max Conc. Mg/mL Max Conc. Milimet Solubility

1eq. HCl	30.74	100
DMSO	30.74	100

Preparing Stock Solutions for (R)-ZINC 3573

The following data is based on the sản phẩm molecular weight 307.4. Batch specific molecular weights may vary from batch khổng lồ batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

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